PROMETA® -

Continued drug abuse alters the way your brain works. Over time, the brain becomes increasingly dependent on receiving an external supply of brain chemicals. These changes in brain chemistry and function play an important role in the physical and behavioral symptoms of substance dependence, tolerance, withdrawal symptoms, craving, and relapse.

The PROMETA Treatment Program has been designed to address these changes in brain chemistry. To learn more about the science behind the PROMETA Treatment Program, visit these links:

Recent Double-Blind Study Shows PROMETA® Treatment Program Reduced Cravings for Methamphetamine

The Scientific Basis of the PROMETA Treatment Program (pdf - 945Kb)

Open-Label Clinical Study Results Published in Mayo Clinic Proceedings Journal

Ongoing Studies of the PROMETA Treatment Program

An Integrated Treatment Approach (pdf - 1.4M)

How We Get Addicted

from TIME Magazine - Thursday, Jul. 05, 2007 By Michael D. Lemonick

The GABA system is the major inhibitory neurotransmitter system in the brain, which is believed to provide a relaxing, anti-anxiety effect. Alcohol and stimulant abuse can disrupt the function of the GABA system, which may contribute to the development of cravings and anxiety. Cravings and anxiety can become part of a daily or weekly cycle, emerging when the effect of the drugs or alcohol wear off, and may become a driving force in continued alcohol and drug use.

POTENTIAL CONSEQUENCES OF ALTERED GABA FUNCTION

Cravings	Sleep disturbance
Anxiety	Increased tolerance
Irritability

ADDRESSING CHANGES TO GABA RECEPTORS MAY HELP YOUR RECOVERY
Restoring the altered GABA receptor may help relieve the cravings and anxiety associated with substance dependence. Relieving these physical symptoms may allow you to better engage in the psychological and social parts of your recovery, giving you a better chance of sustained sobriety.

For a more in-depth study of GABA's role in methamphetamine addiction visit the following link:

The Role of GABA in Methamphetamine Addiction